Bacillus subtilis HU58 – the key ingredient in MiBiotix Antibiotic Therapy AT – has the ability to produce over 12 strong antibiotics in the intestine which helps with balancing intestinal microflora. They do this by fighting off harmful bacteria in the body, affecting their ability to colonise and increasing the growth of natural good bacteria. Bacillus subtilis spores are highly resistant to temperature, extreme pH and gastric acid. They also secrete antimicrobials and stimulate the immune system. Bacillus subtilis HU58 is the only probiotic that is proven to withstand broad spectrum antibiotics delivering 100% of its dose to the small intestine. With this in mind, it can be taken at the same time as the antibiotic thereby prescribed giving the practitioner 100% compliance of recommendation.

Bacillus subtilis HU58, not only produces nutrients such as Vitamin B and Vitamin K2, it also produces a healthy compound called Nattokinase, which has been shown to lower cholesterol, reduce blood pressure and also reduce risk of severe clotting.

Studies have shown that B.subtilis has a positive effect on the maintenance of the normal intestinal flora whilst taking antibiotics and helps with the treatment and prevention of acute intestinal infections

Probiotics are the living microorganisms that provide health benefits to the recipient. Lactobacillus and Bifidobacterium genera have been used since long for the competitive exclusion of pathogens from the gut. However, their limitations such as sensitivity to gastric acid, temperature, slow growth, and specific stability conditions lead to search for a novel probiotic that is stable through its shelf‑life as well as during gastrointestinal transit; hence, offering better efficacy. Bacillus bacteria have strong scientific data which substantiates the validity of the use as preferred probiotics. In recent times, there has been significant progress in scientific evaluation and studies on probiotic Bacillus subtilis, revealing possible mechanisms of action like antimicrobial effect by synthesis of antimicrobial substances, antidiarrheal effect, immunostimulatory effect, competitive exclusion of pathogens, prevention of intestinal inflammation, and normalization of intestinal flora. Numerous clinical studies on B. subtilis have shown its promising efficacy in the treatment and prevention of diarrhea of various etiologies. B. subtilis is certified as generally recognized as safe by Food and Drug Administration and features in the European Food Safety Authority Qualified Presumption of Safety, hence suggesting as safe for human use. All of these beneficial attributes make B. subtilis the most attractive probiotic species for various clinical conditions.

MiBiotix Antibiotic Therapy AT balances the gut, positively affects the composition of the microbiota by forming endospores, supports a healthy immune system, contributes to a healthy digestive system, supports the production of beneficial enzymes in the gut which is critical for digestive and gastrointestinal health and reduces antibiotic associated diarrhoea (AAD).